Uji Efek Penurunan Glukosa Darah Air Perasan Buah Jambu Biji(Psidium guajava L.) pada Mencit (Mus musculus) yang diberikanGlukosa per Oral

Abstract

Guava has been known as traditional medicine. Guava contains tannin which might have hypoglycemic activity. In thisresearch, twenty mice were divided into five groups. Group I was giving aquadest as negative control, group II wasgiving acarbose as positive control, and group III, IV, V were giving water extortion on 20%, 40%, and 80% concentrationfor each. After thirty minutes of treatment, all of mice were induced to hyperglycemic state by giving high concentrationof glucose. After thirty minutes of hyperglycemic induction, blood glucose level was examined by enzymatic method.This research shows that there were a significant difference (p<0, 05) of blood glucose level in mice giving waterextortion of guava in 20% and 80% concentration. In other hands, water extortion of guava in 40% concentration wasnot difference significantly. The research conclude that water extortion of guava could decrease blood glucose levelon mice in concentration of 20% and 80% and 20% was the optimal concentration.